Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CES2 | O00748 | 1/20 | 0.71 |
| ▸ | CES1 | P23141 | 1/20 | 0.71 |
| ▸ | CASP6 | P55212 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668892 | 1.00 | TSHR (1.00) | TSHRCES2CES1CASP6LMNA | |
| Hydrochloric Acid SCHEMBL11517993 | 0.98 | TSHR (0.96) | TSHRCES2CES1CASP6LMNA | |
| Ammonia Solution, Strong SCHEMBL27660564 | 0.98 | TSHR (0.96) | TSHRCES2CES1CASP6LMNA | |
| Diethylamine SCHEMBL28105871 | 0.89 | TSHR (0.79) | TSHRCES2CES1CASP6LMNA | |
| Diethylamine SCHEMBL28029754 | 0.88 | TSHR (0.77) | TSHRCES2CES1CASP6LMNA | |
| SCHEMBL17303445 | 0.87 | TSHR (0.77) | TSHRCES2CES1LMNAMEN1 | |
| SCHEMBL1978668 | 0.87 | TSHR (0.75) | TSHRCES2CES1CASP6LMNA | |
| SCHEMBL12228039 | 0.86 | TSHR (0.76) | TSHRCES2CES1CASP6LMNA | |
| SCHEMBL30041934 | 0.85 | TSHR (0.74) | TSHRCES2CES1LMNAMEN1 | |
| SCHEMBL571521 | 0.85 | TSHR (0.74) | TSHRCES2CES1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 973 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-119080334-A | Comprehensive utilization method of nitric acid containing organic matters | 山东友道化学有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118515568-B | Preparation method of 3-chloro-2-methylaniline | 天津深蓝工程技术有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118515568-A | Preparation method of 3-chloro-2-methylaniline | 天津深蓝工程技术有限公司 | 2024-08-20 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | claimed |
| EP-3692101-B1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTR S R L (IT) | 2022-01-12 | — | — | EP | claimed |
| CN-112745300-A | Method for preparing N- (5-carboxyl-2-methylphenyl) -4- (3-pyridine) -2-pyrimidinamine | 杭州浙中医药科技有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-112250796-A | Preparation method of BX/SGPS nitro-p-methyl benzoate-g-AM/MA | 桂林理工大学 | 2021-01-22 | — | — | CN | claimed |
| CN-112175140-A | Synthesis method of active BX/SGPS quaternary graft copolymerization derivative | 桂林理工大学 | 2021-01-05 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| WO-2003102153-A2 | CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER | AVOLIX PHARMACEUTICALS (US) | 2003-12-11 | — | — | WO | claimed |
| US-RE34272-E | Oxalic acid, a thiocyanate salt, and a nitrobenzenesulfonate salt | REM CHEMICALS, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0395815-B1 | METHOD AND COMPOSITION FOR REFINEMENT OF METAL SURFACES | REM CHEMICALS, INC. (US) | 1993-06-02 | — | — | EP | claimed |
| US-5191010-A | Emulsion having dye developing property | NIPPON ZEON CO., LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0395815-A1 | Method and composition for refinement of metal surfaces | REM CHEMICALS, INC. (US) | 1990-11-07 | — | — | EP | claimed |
| US-4906327-A | Method and composition for refinement of metal surfaces | REM CHEMICALS, INC. (US) | 1990-03-06 | — | — | US | claimed |
| US-4601920-A | DISSOLVING METAL AROMATIC CARBOXYLATE IN ORGANIC SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1986-07-22 | — | — | US | claimed |
| US-4159208-A | REACTING ALKALI METAL SALT OF AN AROMATIC CARBOXYLIC ACID AND A METAL SALT IN THE PRESENCE OF CLAY AND ALUMINUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1979-06-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | TSHR 4082/4885CES2 2351/4885CES1 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.