Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17723978 | 0.93 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL17724006 | 0.90 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17723979 | 0.90 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17724016 | 0.90 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17724038 | 0.86 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL23316641 | 0.83 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17723983 | 0.82 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17724073 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17724068 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3R1PIK3CBMERTK | |
| SCHEMBL17723980 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036293-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| EP-3224248-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |
| EP-3224248-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |
| US-10328060-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2019-06-25 | — | — | US | disclosed |
| US-10328060-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180036293-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
| US-20180036293-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
| WO-2016066142-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036293-A1 | CERTAIN PROTEIN KINASE INHIBITORS | AKT1, PIK3CA, AKT3 | PIK3CD 6/4885PIK3CG 16/4885PIK3R1 31/4885 |
| US-10328060-B2 | Certain protein kinase inhibitors | AKT1, PIK3CA, AKT3 | PIK3CD 6/4885PIK3CG 16/4885PIK3R1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.