Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316461 | 0.91 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL23316453 | 0.90 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBMERTKPIK3R1 | |
| SCHEMBL23316634 | 0.87 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL17724006 | 0.85 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBMERTKPIK3R1 | |
| SCHEMBL17724016 | 0.85 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBMERTKPIK3R1 | |
| SCHEMBL17401160 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CB | |
| SCHEMBL17397179 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CB | |
| SCHEMBL17401103 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CB | |
| SCHEMBL17723974 | 0.83 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3CBMERTKPIK3R1 | |
| SCHEMBL23316419 | 0.80 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224248-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |