Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725090 | 0.89 | ELANE (0.40) | L3MBTL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL18973482 | 0.87 | BTN3A1 (0.49) | NPC1RAB9APPARAL3MBTL1LMNA | |
| SCHEMBL22065045 | 0.82 | POLB (0.42) | NPC1RAB9APPARAL3MBTL1LMNA | |
| SCHEMBL18512900 | 0.80 | ELANE (0.55) | LMNAALDH1A1ELANETP53ATM | |
| SCHEMBL18961792 | 0.80 | ELANE (0.55) | LMNAALDH1A1ELANETP53ATM | |
| SCHEMBL13921734 | 0.80 | ELANE (0.55) | LMNAALDH1A1ELANETP53ATM | |
| SCHEMBL18067131 | 0.78 | ALDH1A1 (0.43) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18067130 | 0.78 | ALDH1A1 (0.43) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22065160 | 0.77 | BTN3A1 (0.48) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL22065158 | 0.77 | BTN3A1 (0.48) | ALDH1A1HPGDELANETP53AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016068341-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2016-05-06 | — | — | WO | disclosed |