Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.62 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.50 |
| ▸ | SELL | P14151 | 2/20 | 0.48 |
| ▸ | SELP | P16109 | 2/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177287 | 1.00 | CASR (0.62) | CASRLNPEPSELLSELPSELE | |
| SCHEMBL2523349 | 0.82 | CASR (0.65) | CASRSELLSELPSELEALDH1A1 | |
| SCHEMBL7902676 | 0.77 | LTA4H (0.60) | ALDH1A1S1PR1S1PR3 | |
| SCHEMBL14426473 | 0.77 | SELL (0.65) | CASRSELLSELPSELEALDH1A1 | |
| SCHEMBL11038421 | 0.77 | LTA4H (0.60) | ALDH1A1S1PR1S1PR3 | |
| SCHEMBL14471910 | 0.76 | CASR (1.00) | CASRSELLSELPALDH1A1MEN1 | |
| SCHEMBL11037758 | 0.76 | CASR (0.56) | CASRALDH1A1MEN1KMT2AS1PR1 | |
| SCHEMBL11037760 | 0.76 | CASR (0.56) | CASRALDH1A1MEN1KMT2AS1PR1 | |
| SCHEMBL14426833 | 0.75 | SELL (0.62) | CASRSELLSELPSELEMEN1 | |
| SCHEMBL9335895 | 0.75 | CASR (0.43) | CASRLNPEPERAP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |