Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090107 | 0.90 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17922751 | 0.90 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| Heptane SCHEMBL2518470 | 0.82 | TSHR (0.47) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL12288169 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL21835638 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL21835634 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL21835636 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL21835666 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL21835664 | 0.79 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL16796700 | 0.79 | TSHR (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951208-B2 | Silica shielding agents and related methods | BRIDGESTONE CORPORATION (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20160130423-A1 | Silica Shielding Agents And Related Methods | BRIDGESTONE CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |