Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090107 | 1.00 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL17728693 | 0.90 | TSHR (0.32) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL5701571 | 0.82 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL5701529 | 0.82 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL5199634 | 0.80 | — | — | |
| SCHEMBL3798228 | 0.77 | TSHR (0.36) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| Heptane SCHEMBL28749900 | 0.77 | TSHR (0.53) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL19707640 | 0.77 | MEN1 (0.44) | TSHRLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL727806 | 0.76 | TSHR (0.40) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL946330 | 0.76 | LMNA (0.41) | TSHRTHRBLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200876-A1 | CROSS-LINKED COMPOSITION AND METHOD OF FORMING THE SAME | DOW CORNING CORPORATION (US) | 2016-07-14 | — | — | US | disclosed |