SCHEMBL177315

SCHEMBL177315

O=C(CC(=O)OC(=O)CC(O)C(=O)O)OC(=O)CC(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
TET2 Q6N021 6/20 0.43
TET3 O43151 2/20 0.43
TET1 Q8NFU7 1/20 0.43
OR51E2 Q9H255 1/20 0.40
KDM4A O75164 2/20 0.36
KDM4C Q9H3R0 2/20 0.36
KDM2A Q9Y2K7 2/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
KMO O15229 1/20 0.32
GPR84 Q9NQS5 3/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14920141 0.98 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL11219458 0.93 SMN1; SMN2 (0.57) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28219168 0.87 SMN1; SMN2 (0.43) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6753717 0.86 SMN1; SMN2 (0.50) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL27210192 0.84 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL2036591 0.84 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL9306134 0.84 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6863771 0.83 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28786289 0.83 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL11094951 0.82 TET2 (0.47) SMN1; SMN2TET2TET3TET1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438295-A Methods and compositions for culturing pluripotent cell suspensions 生命技术公司 2023-07-14 CN disclosed
WO-2021215852-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION (주)셀트리온 (KR) 2021-10-28 WO disclosed
CN-105334283-B Simultaneous Determination reconstituted tobacco oxalate, amber acid radical, the sample-pretreating method of sulfate radical and phosphate radical 广东中烟工业有限责任公司 2018-03-27 CN disclosed
CN-105372371-A Ion chromatography method for simultaneous determination of oxalic ion, succinate ion, sulfate ion and phosphate ion in reconstituted tobacco and application thereof CHINA TOBACCO GUANGDONG IND CO 2016-03-02 CN disclosed
CN-105334283-A Sample pretreatment method for simultaneous determination of oxalic acid, succinic acid, sulfuric acid and phosphate radicals in regenerated tobacco leaves through ion chromatography CHINA TOBACCO GUANGDONG IND CO 2016-02-17 CN disclosed
EP-2344487-A1 HEPATITIS C INHIBITOR COMPOUNDS Boehringer Ingelheim International GmbH (DE) 2011-07-20 EP disclosed
EP-2235173-A2 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2010-10-06 EP disclosed
WO-2010034105-A1 HEPATITIS C INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 WO disclosed
WO-2009085935-A2 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2009-07-09 WO disclosed