SCHEMBL6863771

SCHEMBL6863771

O=C(CC(O)C(=O)O)OC(=O)C(=O)OC(=O)CC(O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
TET2 Q6N021 6/20 0.44
TET3 O43151 2/20 0.44
TET1 Q8NFU7 1/20 0.44
OR51E2 Q9H255 1/20 0.42
KDM4A O75164 2/20 0.37
KDM4C Q9H3R0 2/20 0.37
KDM2A Q9Y2K7 2/20 0.37
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
CA4 P22748 1/20 0.33
KMO O15229 1/20 0.32
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11219458 0.90 SMN1; SMN2 (0.57) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL5404110 0.87 SMN1; SMN2 (0.44) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28786289 0.85 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL1828775 0.83 SMN1; SMN2 (0.41) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6753717 0.83 SMN1; SMN2 (0.50) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL177315 0.83 SMN1; SMN2 (0.50) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28189997 0.82 TET2 (0.44) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL2036591 0.81 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL9306134 0.81 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6431576 0.81 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800218-B2 Abrasive free formulations for chemical mechanical polishing of copper and associated materials and method of using same ADVANCED TECHNOLOGY MATERIALS, INC. 2004-10-05 US claimed
US-4026711-A TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM PHOSPHATE-CARBOXYLATE, UREA AMERICAN CYANAMID COMPANY (US) 1977-05-31 US claimed