SCHEMBL1773188

SCHEMBL1773188

CCC(C)[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.50
CIB1 Q99828 4/20 0.49
PSMB11 A5LHX3 1/20 0.48
PSMA7 O14818 1/20 0.48
PSMB1 P20618 1/20 0.48
PSMA1 P25786 1/20 0.48
PSMA2 P25787 1/20 0.48
PSMA3 P25788 1/20 0.48
PSMA4 P25789 1/20 0.48
PSMB8 P28062 1/20 0.48
PSMB9 P28065 1/20 0.48
PSMA5 P28066 1/20 0.48
PSMB4 P28070 1/20 0.48
PSMB6 P28072 1/20 0.48
PSMB5 P28074 1/20 0.48
PSMB10 P40306 1/20 0.48
PSMB3 P49720 1/20 0.48
PSMB2 P49721 1/20 0.48
PSMA6 P60900 1/20 0.48
PSMA8 Q8TAA3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32676347 0.94 PSMB11 (0.53) ELANECIB1PSMB11PSMA7PSMB1
SCHEMBL1519049 0.88 ITGAV (0.47) ELANE
SCHEMBL28057731 0.88 ELANE (0.50) ELANEPSMB11PSMA7PSMB1PSMA1
SCHEMBL29779778 0.88 GHSR (0.52) ST14
SCHEMBL28240936 0.88 GHSR (0.52) ST14
SCHEMBL29886515 0.87 ELANE (0.57) ELANEPSMB11PSMA7PSMB1PSMA1
Axinastatin 5 SCHEMBL8569878 0.87 HDAC8 (0.48)
SCHEMBL29412929 0.86 HDAC4 (0.54)
Hymenistatin 1 SCHEMBL25456477 0.86 HDAC8 (0.51)
Hymenistatin 1 SCHEMBL29593232 0.86 HDAC8 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2229403-B1 RECOVERY OF HYDROPHOBIC PEPTIDES FROM OILS UNIV SASKATCHEWAN (CA) 2013-10-16 EP disclosed
US-8383172-B2 Recovery of hydrophobic peptides from oils UNIVERSITY OF SASKATCHEWAN (CA) 2013-02-26 US disclosed
US-20110111073-A1 RECOVERY OF HYDROPHOBIC PEPTIDES FROM OILS UNIVERSITY OF SASKATCHEWAN (CA) 2011-05-12 US disclosed
EP-2229403-A1 RECOVERY OF HYDROPHOBIC PEPTIDES FROM OILS University of Saskatchewan (CA) 2010-09-22 EP disclosed
WO-2009079792-A1 RECOVERY OF HYDROPHOBIC PEPTIDES FROM OILS UNIVERSITY OF SASKATCHEWAN (CA) 2009-07-02 WO disclosed