Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19294597 | 0.84 | ALDH1A1 (0.35) | MAOBMAOAKDM4EALOX12SMN1; SMN2 | |
| SCHEMBL17776322 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL17776273 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL19658247 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL13635161 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL10086616 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL17776321 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL18751700 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL17776275 | 0.83 | PSMB8 (0.32) | ALOX12 | |
| SCHEMBL410465 | 0.83 | PSMB8 (0.32) | ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570250-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | Life Technologies Corporation (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180355098-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation | 2018-12-13 | — | — | US | disclosed |
| US-10087280-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | Life Technologies Corporation (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3215515-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation | 2017-08-31 | — | — | US | disclosed |
| WO-2016073052-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation (US) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570250-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | DDOST, DDT, DAD1 | TSHR 4755/4885MAOB 952/4885MAOA 1859/4885 |
| US-20180355098-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | DDOST, DDT, DAD1 | TSHR 4755/4885MAOB 952/4885MAOA 1859/4885 |
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | DDOST, DDT, DAD1 | TSHR 4755/4885MAOB 952/4885MAOA 1859/4885 |
| US-10087280-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | DDOST, DDT, DAD1 | TSHR 4755/4885MAOB 952/4885MAOA 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.