Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17732129 | 0.83 | AR (0.43) | SMN1; SMN2KDM4CLMNAP2RX7 | |
| SCHEMBL5023203 | 0.74 | TBXA2R (0.45) | HTTKDM4CCOPS5NPSR1LMNA | |
| SCHEMBL20356667 | 0.69 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2KDM4CCOPS5P2RX7 | |
| SCHEMBL17732132 | 0.69 | MEN1 (0.41) | LMNAKMT2AMEN1 | |
| SCHEMBL1682174 | 0.68 | P2RX7 (0.52) | HTTSMN1; SMN2NPSR1LMNACYP3A4 | |
| SCHEMBL5434889 | 0.68 | NPSR1 (0.46) | HTTKDM4CNPSR1LMNACYP1A2 | |
| SCHEMBL21526053 | 0.67 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2KDM4CCOPS5P2RX7 | |
| SCHEMBL27810368 | 0.66 | MRGPRX4 (0.56) | SMN1; SMN2KDM4CLMNATSHRTBXA2R | |
| SCHEMBL2097653 | 0.66 | IDO1 (0.65) | HTTSMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL21526072 | 0.65 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2KDM4CCOPS5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215136-A1 | ANTIVIRAL AGENTS DIRECTED AGAINST RESPIRATORY SYNCYTIAL VIRUS | Centre National de la Recherche Scientifique (CNRS) (FR) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016071470-A1 | ANTIVIRAL AGENTS DIRECTED AGAINST RESPIRATORY SYNCYTIAL VIRUS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2016-05-12 | — | — | WO | disclosed |