⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17732130 | 0.86 | HCAR2 (0.47) | — | |
| SCHEMBL17732132 | 0.85 | MEN1 (0.41) | — | |
| SCHEMBL23453728 | 0.84 | MEN1 (0.57) | — | |
| SCHEMBL16260378 | 0.70 | AR (0.61) | — | |
| SCHEMBL5900723 | 0.69 | MEN1 (0.57) | — | |
| SCHEMBL17732131 | 0.69 | HTT (0.45) | — | |
| SCHEMBL23453747 | 0.69 | AR (0.50) | — | |
| SCHEMBL23453720 | 0.69 | GRIA1 (0.48) | — | |
| SCHEMBL23453748 | 0.69 | MEN1 (0.57) | — | |
| SCHEMBL22609275 | 0.69 | NPC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215136-A1 | ANTIVIRAL AGENTS DIRECTED AGAINST RESPIRATORY SYNCYTIAL VIRUS | Centre National de la Recherche Scientifique (CNRS) (FR) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016071470-A1 | ANTIVIRAL AGENTS DIRECTED AGAINST RESPIRATORY SYNCYTIAL VIRUS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2016-05-12 | — | — | WO | disclosed |