Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.67 |
| ▸ | XDH | P47989 | 7/20 | 0.67 |
| ▸ | BCHE | P06276 | 5/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.67 |
| ▸ | MAOA | P21397 | 5/20 | 0.67 |
| ▸ | ACHE | P22303 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 4/20 | 0.67 |
| ▸ | CA7 | P43166 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Apigenin SCHEMBL3133565 | 0.92 | ABCB1 (0.78) | KMT2AFTOABCB1CYP3A4MAPT | |
| Quercetin SCHEMBL18555282 | 0.91 | KMT2A (0.68) | KMT2AFTOABCB1CYP3A4MAPT | |
| Myricetin SCHEMBL14691164 | 0.88 | KMT2A (0.60) | KMT2AFTOABCB1CYP3A4MAPT | |
| Myricetin SCHEMBL4983336 | 0.87 | KMT2A (0.72) | KMT2AFTOABCB1CYP3A4MAPT | |
| Kaempferol SCHEMBL28180527 | 0.87 | ABCB1 (0.69) | KMT2AFTOABCB1CYP3A4MAPT | |
| Luteolin SCHEMBL8161993 | 0.86 | MEN1 (0.72) | KMT2AFTOABCB1CYP3A4MAPT | |
| Morin SCHEMBL28120180 | 0.86 | CYP3A4 (0.73) | KMT2AFTOABCB1CYP3A4MAPT | |
| Quercetin SCHEMBL4303275 | 0.85 | MEN1 (0.74) | KMT2AFTOABCB1CYP3A4MAPT | |
| Apigenin SCHEMBL3860131 | 0.84 | CYP3A4 (0.91) | KMT2AFTOABCB1CYP3A4MAPT | |
| Genistein SCHEMBL12488651 | 0.84 | MAPT (0.65) | KMT2AFTOABCB1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016072522-A1 | NOVEL THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | 国立大学法人 長崎大学 | 2016-05-12 | — | — | WO | disclosed |