Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.68 |
| ▸ | MEN1 | O00255 | 13/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 11/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 11/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.68 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.68 |
| ▸ | XDH | P47989 | 9/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | TP53 | P04637 | 7/20 | 0.68 |
| ▸ | RECQL | P46063 | 7/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quercetin SCHEMBL4303275 | 0.93 | MEN1 (0.74) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Kaempferol SCHEMBL17732292 | 0.91 | KMT2A (0.67) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Luteolin SCHEMBL8161993 | 0.90 | MEN1 (0.72) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Quercetin SCHEMBL6440211 | 0.88 | MEN1 (0.68) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Myricetin SCHEMBL14691164 | 0.87 | KMT2A (0.60) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Quercetin SCHEMBL8116614 | 0.87 | MEN1 (0.77) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Quercetin SCHEMBL2407213 | 0.87 | MEN1 (0.81) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Quercetin SCHEMBL3958393 | 0.86 | MEN1 (0.87) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Apigenin SCHEMBL3133565 | 0.84 | ABCB1 (0.78) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 | |
| Quercetin SCHEMBL4173190 | 0.84 | MEN1 (0.87) | KMT2AMEN1CYP3A4CYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033060-A1 | COMPOSITION FOR TREATING DRY EYE DISEASES AND SJÖGREN'S SYNDROME | UNIVERSITY OF MACAU (CN) | 2017-03-02 | — | — | WO | claimed |