Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329885 | 1.00 | KMT2A (0.60) | KMT2AHTR2CKDM4CCA1CA2 | |
| Hydrochloric Acid SCHEMBL330054 | 0.99 | KMT2A (0.59) | KMT2AHTR2CKDM4CCA1CA2 | |
| SCHEMBL25316370 | 0.85 | CA1 (0.54) | KMT2AHTR2CKDM4CCA1CA2 | |
| SCHEMBL10837762 | 0.84 | HTR2C (0.52) | KMT2AHTR2CKDM4CCA1CA2 | |
| SCHEMBL329884 | 0.83 | HTR2C (0.51) | KMT2AHTR2CKDM4CCA1CA2 | |
| SCHEMBL14355542 | 0.83 | CA1 (0.52) | KMT2AHTR2CKDM4CCA1CA2 | |
| SCHEMBL25412770 | 0.82 | KMT2A (0.47) | KMT2AHTR2CKDM4CRAB9AKDM1A | |
| SCHEMBL10348794 | 0.82 | ADRB2 (0.52) | KMT2AHTR2COPRM1 | |
| SCHEMBL3870396 | 0.81 | PPARD (0.52) | KMT2AHTR2CCA1CA2CA7 | |
| SCHEMBL21346200 | 0.81 | KDM4E (0.60) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3018126-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-05-11 | — | — | EP | disclosed |