Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 4/20 | 0.38 |
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614361 | 0.88 | ALDH1A1 (0.42) | CYP1A2CA1CA2CA9ERBB2 | |
| SCHEMBL667035 | 0.86 | MPL (0.33) | MPLCA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL2018837 | 0.85 | MPL (0.51) | MPLCTRCCYP1A2ERBB2FYN | |
| SCHEMBL20138548 | 0.84 | MPL (0.50) | MPLCTRCCYP1A2ERBB2FYN | |
| SCHEMBL16380316 | 0.83 | MPL (0.33) | MPLCYP1A2CA1CA2CA9 | |
| SCHEMBL1285825 | 0.79 | ALDH1A1 (0.46) | CYP1A2CA1CA2CA9ERBB2 | |
| SCHEMBL30672506 | 0.79 | ALDH1A1 (0.46) | CYP1A2CA1CA2CA9ERBB2 | |
| SCHEMBL29440260 | 0.78 | ALDH1A1 (0.52) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL13736031 | 0.78 | ALDH1A1 (0.52) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL29104759 | 0.77 | ALDH1A1 (0.50) | CYP1A2ERBB2FYNMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181160-B1 | HPTS-MONO CYS-MA POLYMERIZABLE FLUORESCENT DYES FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED INC (US) | 2016-05-11 | — | — | EP | disclosed |