Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023973 | 1.00 | ACHE (0.57) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL12530818 | 1.00 | ACHE (0.57) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL17431977 | 0.93 | ACHE (0.59) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL15158621 | 0.93 | ACHE (0.55) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL10819280 | 0.93 | ACHE (0.55) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL15160079 | 0.93 | ACHE (0.55) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL16158099 | 0.92 | ACHE (0.51) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL18180593 | 0.92 | ACHE (0.51) | ACHELPAR1LPAR3TLR2 | |
| SCHEMBL19266108 | 0.91 | ACHE (0.58) | ACHE | |
| SCHEMBL25005592 | 0.91 | LPAR1 (0.54) | ACHELPAR1LPAR3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225621-A1 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | Arbutus Biopharma Corporation (CA) | 2017-10-04 | — | — | EP | disclosed |
| EP-3100718-A1 | IMPROVED COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | Arbutus Biopharma Corporation (CA) | 2016-12-07 | — | — | EP | disclosed |
| EP-2224912-B1 | IMPROVED COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORP (CA) | 2016-05-11 | — | — | EP | disclosed |