Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12080866 | 0.92 | ATM (0.41) | ATMNR1H3MAOBHCRTR2MEN1 | |
| SCHEMBL2240547 | 0.91 | ATM (0.38) | ATMNR1H3SLC22A12MAOBHCRTR2 | |
| SCHEMBL176720 | 0.91 | ATM (0.38) | ATMNR1H3SLC22A12MAOBHCRTR2 | |
| SCHEMBL177178 | 0.91 | ATM (0.40) | ATMNR1H3MAOBHCRTR2MEN1 | |
| SCHEMBL2240314 | 0.88 | ATM (0.39) | ATMNR1H3SLC22A12MAOBHCRTR2 | |
| SCHEMBL176906 | 0.88 | ATM (0.39) | ATMNR1H3SLC22A12MAOBHCRTR2 | |
| SCHEMBL2306925 | 0.85 | ATM (0.39) | ATMNR1H3MAOBHCRTR2MEN1 | |
| SCHEMBL3337661 | 0.85 | ATM (0.39) | ATMNR1H3MAOBHCRTR2MEN1 | |
| SCHEMBL2239951 | 0.83 | ATM (0.37) | ATMNR1H3MAOBHCRTR2MEN1 | |
| SCHEMBL11897328 | 0.83 | ATM (0.37) | ATMNR1H3MAOBHCRTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |