Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239951 | 0.92 | ATM (0.37) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL2239948 | 0.92 | ATM (0.37) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL177335 | 0.91 | ATM (0.41) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL12080866 | 0.91 | ATM (0.41) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL177347 | 0.89 | ATM (0.38) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL3337661 | 0.83 | ATM (0.39) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL2306925 | 0.83 | ATM (0.39) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL177355 | 0.83 | HCRTR2 (0.47) | ATMNR1H3HCRTR2MAOBTSHR | |
| SCHEMBL176720 | 0.83 | ATM (0.38) | ATMNR1H3HCRTR2MAOBMEN1 | |
| SCHEMBL2240547 | 0.83 | ATM (0.38) | ATMNR1H3HCRTR2MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |