Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11928883 | 0.70 | MRGPRX2 (0.40) | MRGPRX2MAOAMAOB | |
| SCHEMBL25015134 | 0.70 | MRGPRX2 (0.40) | MRGPRX2MAOAMAOB | |
| SCHEMBL8297090 | 0.67 | — | — | |
| SCHEMBL19075425 | 0.65 | MRGPRX2 (0.37) | MRGPRX2MAOAMAOB | |
| SCHEMBL19141400 | 0.65 | MRGPRX2 (0.37) | MRGPRX2MAOAMAOB | |
| SCHEMBL19597416 | 0.64 | — | — | |
| SCHEMBL19723365 | 0.64 | MRGPRX2 (0.36) | MRGPRX2 | |
| SCHEMBL24633930 | 0.62 | — | — | |
| SCHEMBL19647606 | 0.61 | MRGPRX2 (0.34) | MRGPRX2MAOAMAOB | |
| SCHEMBL18034707 | 0.60 | MRGPRX2 (0.33) | MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |