Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 16/20 | 0.86 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16436992 | 0.92 | CXCR4 (0.97) | CXCR4CXCL12POLBSIGMAR1ALDH1A1 | |
| SCHEMBL9885528 | 0.89 | CXCR4 (0.85) | CXCR4CXCL12 | |
| SCHEMBL16436991 | 0.84 | CXCR4 (0.82) | CXCR4CXCL12POLBSIGMAR1ALDH1A1 | |
| SCHEMBL21799448 | 0.84 | ALDH1A1 (0.59) | CXCR4POLBALDH1A1 | |
| SCHEMBL9884969 | 0.81 | CXCR4 (0.76) | CXCR4CXCL12POLBSIGMAR1ALDH1A1 | |
| SCHEMBL9885505 | 0.81 | CXCR4 (0.76) | CXCR4CXCL12 | |
| SCHEMBL23023007 | 0.79 | CXCR4 (0.54) | CXCR4CXCL12SIGMAR1 | |
| SCHEMBL30219100 | 0.76 | MC4R (0.58) | CXCR4SIGMAR1 | |
| SCHEMBL9252404 | 0.76 | ALDH1A1 (0.68) | CXCR4POLBALDH1A1 | |
| SCHEMBL11509945 | 0.76 | ALDH1A1 (0.68) | CXCR4POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890703-B1 | PYRIMIDINE COMPOUNDS AS CHEMOKINE RECEPTORS INHIBITORS | TAIGEN BIOTECHNOLOGY CO LTD (TW) | 2016-05-11 | — | — | EP | disclosed |