Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446411 | 0.86 | CFTR (0.58) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL2601115 | 0.84 | CFTR (0.63) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL17069338 | 0.84 | CFTR (0.63) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL17071838 | 0.84 | CFTR (0.63) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL14283944 | 0.84 | CFTR (0.63) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL5023967 | 0.83 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL5999497 | 0.82 | CFTR (0.61) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL6581164 | 0.82 | TBXAS1 (0.53) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL5998629 | 0.81 | TBXAS1 (0.52) | TBXAS1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL14242083 | 0.81 | SLC6A2 (0.70) | CYP17A1ESR1SMN1; SMN2CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066337-A | 5-hydroxypyrimidine-4-carboxamide compounds | DAIICHI SANKYO CO LTD | 2011-05-18 | — | — | CN | disclosed |
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | CYP17A1 747/4885ESR1 665/4885PDCD1 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.