SCHEMBL1773565

SCHEMBL1773565

C=CCN1C(=O)C(=C2SC=C(C)N2CC)SC1=S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 12/20 0.60
▸ MEN1 O00255 11/20 0.60
▸ POLB P06746 4/20 0.60
▸ ALDH1A1 P00352 6/20 0.48
▸ HSD17B10 Q99714 3/20 0.48
▸ CASP1 P29466 2/20 0.48
▸ HCRTR1 O43613 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ BRCA1 P38398 1/20 0.48
▸ MYC P01106 1/20 0.44
▸ MAX P61244 1/20 0.44
▸ MMP13 P45452 2/20 0.42
▸ MAPT P10636 6/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ MAPK1 P28482 3/20 0.39
▸ PKM P14618 1/20 0.39
▸ USP2 O75604 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14273144 0.88 KMT2A (0.60) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL10036089 0.84 KMT2A (0.46) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL11878875 0.80 KMT2A (0.48) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL11878882 0.80 KMT2A (0.48) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL10036087 0.78 ALDH1A1 (0.51) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL11319531 0.78 KMT2A (0.57) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL11319535 0.78 KMT2A (0.57) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL12194182 0.76 MEN1 (0.58) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL1773568 0.71 KMT2A (0.52) KMT2AMEN1POLBALDH1A1HSD17B10
SCHEMBL10036070 0.69 MAPT (0.55) KMT2AMEN1POLBALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039144-A1 OPTICAL DATA RECORDING MEDIA HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2010-04-08 — — WO claimed
WO-2009126167-A1 OPTICAL DATA RECORDING MEDIA AND METHODS FOR RECORDING AND READING DATA THEREON HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-10-15 — — WO claimed
WO-2006049732-A1 COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2006-05-11 — — WO claimed
US-20060093958-A1 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-05-04 — — US claimed
US-20060078832-A1 Compositions for multi-color, light activated imaging HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-04-13 — — US claimed
EP-3442780-B1 PARTICULATE BUILD MATERIAL HEWLETT PACKARD DEVELOPMENT CO (US) 2024-07-10 — — EP disclosed
CN-108602262-B Granular building material 惠普发展公司,有限责任合伙企业 2021-07-30 — — CN disclosed
US-10946584-B2 Particulate build material HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-03-16 — — US disclosed
EP-3442780-A1 PARTICULATE BUILD MATERIAL Hewlett-Packard Development Company, L.P. (US) 2019-02-20 — — EP disclosed
US-20190047215-A1 PARTICULATE BUILD MATERIAL HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2019-02-14 — — US disclosed
WO-2017180095-A1 PARTICULATE BUILD MATERIAL HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2017-10-19 — — WO disclosed
US-8283100-B2 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2012-10-09 — — US disclosed
WO-2006073801-A2 COLOR FORMING COMPOSITIONS WITH IMPROVED MARKING SENSITIVITY AND IMAGE CONTRAST AND ASSOCIATED METHODS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2006-07-13 — — WO disclosed
US-20060147833-A1 Color forming compositions with improved marking sensitivity and image contrast and associated methods KASPERCHIK VLADEK P 2006-07-06 — — US disclosed
WO-2006049732-A1 COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2006-05-11 — — WO disclosed
US-20060093958-A1 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-05-04 — — US disclosed
WO-2006043064-A1 PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE MERCK SHARP & DOHME LIMITED (GB) 2006-04-27 — — WO disclosed
WO-2006038996-A1 COLOR FORMING COMPOSITIONS AND ASSOCIATED METHODS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2006-04-13 — — WO disclosed
US-20060078832-A1 Compositions for multi-color, light activated imaging HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-04-13 — — US disclosed
US-20060068315-A1 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-03-30 — — US disclosed
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