Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17733157 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL8393507 | 0.80 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL29919905 | 0.80 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL29862025 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL8391116 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL1402598 | 0.78 | NQO1 (0.48) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL1402280 | 0.78 | NQO1 (0.48) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL1003225 | 0.75 | NQO1 (0.72) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL30949381 | 0.75 | NQO1 (0.72) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL8270248 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643905-B2 | Phenylnaphthol derivatives | TOKUYAMA CORPORATION (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | TOKUYAMA CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | AHR, ARL1, PAH | KDM4E 3611/4885ALDH1A1 889/4885HPGD 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.