⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168948 | 0.84 | — | — | |
| SCHEMBL17641593 | 0.80 | — | — | |
| SCHEMBL27605983 | 0.79 | — | — | |
| SCHEMBL336316 | 0.77 | — | — | |
| SCHEMBL16328954 | 0.77 | — | — | |
| SCHEMBL3354022 | 0.76 | — | — | |
| SCHEMBL8668976 | 0.76 | — | — | |
| SCHEMBL12085968 | 0.76 | — | — | |
| SCHEMBL30871009 | 0.76 | — | — | |
| SCHEMBL1504657 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11478445-B2 | Method for treating acute myeloid leukemia | BIONOMICS LTD. (AU) | 2022-10-25 | — | — | US | disclosed |
| US-20210177797-A1 | METHOD FOR TREATING ACUTE MYELOID LEUKEMIA | BIONOMICS LIMITED (AU) | 2021-06-17 | — | — | US | disclosed |
| CN-107427487-B | Combination treatment regimen | 生态学有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-111447972-A | Method for treating acute myeloid leukemia | 生态学有限公司 | 2020-07-24 | — | — | CN | disclosed |
| US-20200069729-A1 | Combination Therapy for Treating Proliferative Diseases | BIONOMICS, LTD (AU) | 2020-03-05 | — | — | US | disclosed |
| US-10137105-B2 | Combination treatment protocol | BIONOMICS LIMITED (AU) | 2018-11-27 | — | — | US | disclosed |
| EP-2854796-B1 | COMBINATIONS OF A VASCULAR DISRUPTING AGENT AND A HYPOXIA-TARGETING AGENT FOR USE IN THE TREATMENT OF CANCER | BIONOMICS LTD (AU) | 2018-11-14 | — | — | EP | disclosed |
| US-20180289739-A1 | Combination Therapy for Treating Proliferative Diseases | BIONOMICS LTD (AU) | 2018-10-11 | — | — | US | disclosed |
| US-9987293-B2 | Method for treating chronic lymphocytic leukemia | BIONOMICS LIMITED (AU) | 2018-06-05 | — | — | US | disclosed |
| US-20180042887-A1 | COMBINATION TREATMENT PROTOCOL | BIONOMICS LIMITED (AU) | 2018-02-15 | — | — | US | disclosed |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| US-20110130367-A1 | Combination Therapy for Treating Proliferative Diseases | BIONOMICS LIMITED (AU) | 2011-06-02 | — | — | US | disclosed |
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-11-18 | — | — | US | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| US-20100004208-A1 | SUBSTITUTED BENZOFURANS, BENZOTHIOPHENES, BENZOSELENOPHENES AND INDOLES AND THEIR USE AS TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-01-07 | — | — | US | disclosed |
| EP-1848704-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | Bionomics Limited (AU) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084338-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2006-08-17 | — | — | WO | disclosed |
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |