Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560718 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL17109619 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL2515797 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL2515794 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL19644956 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL12202864 | 1.00 | DUT (0.56) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL18671955 | 0.91 | DUT (0.57) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL21418793 | 0.88 | DUT (0.54) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL17560698 | 0.88 | DUT (0.54) | DUTCYP3A4CYP2C9P2RY2P2RY4 | |
| SCHEMBL14420872 | 0.88 | CYP3A4 (0.53) | DUTCYP3A4CYP2C9P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016073756-A1 | DEUTERATED NUCLEOSIDE/TIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2016-05-12 | — | — | WO | disclosed |