SCHEMBL17740484

SCHEMBL17740484

CCCc1cc(F)c(C(=O)Oc2cc(F)c(C#N)c(F)c2)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.44
PTPN11 Q06124 2/20 0.44
PTPN2 P17706 1/20 0.37
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
KMT2A Q03164 2/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
PTGES O14684 2/20 0.33
TOP2A P11388 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
STAT3 P40763 1/20 0.32
ALOX5 P09917 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24492685 0.86 PTPN1 (0.34) PTPN1PTPN11PTPN2MAPTKMT2A
SCHEMBL6569177 0.86 PTPN1 (0.33) PTPN1PTPN11
SCHEMBL6898541 0.86 PTPN1 (0.33) PTPN1PTPN11
SCHEMBL17705320 0.85 MAPT (0.39) PTPN1PTPN11PTPN2NPC1MAPT
SCHEMBL24492667 0.85 RARB (0.37) PTPN1PTPN11MAPTSMN1; SMN2PTGES
SCHEMBL17740480 0.85 NPC1 (0.45) PTPN1PTPN11NPC1MAPTCASP3
SCHEMBL14884236 0.84 PTGES (0.36) PTPN1PTPN11PTGESTOP2ATHRB
SCHEMBL6567817 0.84 PTPN1 (0.31) PTPN1PTPN11STAT3
SCHEMBL6567821 0.84 PTPN1 (0.31) PTPN1PTPN11STAT3
SCHEMBL6567948 0.84 PTPN1 (0.32) PTPN1PTPN11TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed