SCHEMBL17740744

SCHEMBL17740744

CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4cc(N(c5ccccc5)c5ccc(-c6ccc(Br)cc6)cc5)ccc43)cc21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.32
TSPO P30536 2/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17740656 0.95 KDM4E (0.33) HDAC4TSPO
SCHEMBL21158463 0.93 TSPO (0.34) HDAC4TSPO
SCHEMBL21082723 0.91 TSPO (0.35) HDAC4TSPO
SCHEMBL18164782 0.91 KDM4E (0.30)
SCHEMBL15685653 0.91 TSPO (0.36) HDAC4TSPO
SCHEMBL15685651 0.91 TSPO (0.36) HDAC4TSPO
SCHEMBL529225 0.90 KDM4E (0.35) HDAC4TSPOTP53MAPT
SCHEMBL19830273 0.90 KDM4E (0.35) HDAC4TSPO
SCHEMBL15685647 0.90 TSPO (0.38) HDAC4TSPO
SCHEMBL12785788 0.90 KDM4E (0.38) TSPOTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016072691-A1 ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE USING COMPOSITION FOR ORGANIC ELECTRONIC DEVICE 덕산네오룩스 주식회사 2016-05-12 WO disclosed