Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 6/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19093132 | 0.94 | IDO1 (0.51) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL23680166 | 0.91 | IDO1 (0.47) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL17729158 | 0.90 | IDO1 (0.46) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL17729130 | 0.90 | IDO1 (0.56) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL22986523 | 0.90 | IDO1 (0.46) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL21213934 | 0.89 | IDO1 (0.57) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL22730002 | 0.88 | IDO1 (0.56) | PDGFRBIDO1PIK3CACYP2C9CYP3A4 | |
| SCHEMBL17729240 | 0.88 | PDGFRB (0.47) | PDGFRBIDO1PIK3CA | |
| SCHEMBL23699121 | 0.86 | IDO1 (0.44) | PDGFRBIDO1CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17729152 | 0.85 | PIK3CA (0.50) | PDGFRBIDO1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197973-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-07-13 | — | — | US | claimed |
| US-9643972-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-05-09 | — | — | US | claimed |
| EP-3854394-A1 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-107427499-B | Immunomodulator | 弗莱塞斯生物科学公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3215153-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3215153-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20190002472-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2019-01-03 | — | — | US | disclosed |
| US-20190002472-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2019-01-03 | — | — | US | disclosed |
| US-10106546-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2018-10-23 | — | — | US | disclosed |
| US-20180282281-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2018-10-04 | — | — | US | disclosed |
| US-20170197973-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170197973-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170197973-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-07-13 | — | — | US | disclosed |
| US-9643972-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9643972-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9643972-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160137652-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137652-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137652-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2016-05-19 | — | — | US | disclosed |
| WO-2016073770-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10106546-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | PDGFRB 3932/4885IDO1 1/4885PIK3CA 4170/4885 |
| US-20180282281-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | PDGFRB 3932/4885IDO1 1/4885PIK3CA 4170/4885 |
| US-20160137652-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | PDGFRB 3932/4885IDO1 1/4885PIK3CA 4170/4885 |
| US-20190002472-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | PDGFRB 3932/4885IDO1 1/4885PIK3CA 4170/4885 |
| US-20170197973-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | PDGFRB 3932/4885IDO1 1/4885PIK3CA 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.