Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773177 | 0.94 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1GAANOS3 | |
| SCHEMBL1772044 | 0.86 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1GAANOS3 | |
| SCHEMBL12602175 | 0.82 | HPGD (0.51) | TPSAB1TPSD1TPSG1 | |
| Acetic Acid SCHEMBL1773472 | 0.82 | HPGD (0.48) | TPSAB1TPSD1TPSG1 | |
| Acetic Acid SCHEMBL1774293 | 0.81 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL1773421 | 0.80 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1GAANOS3 | |
| SCHEMBL1772704 | 0.78 | TPSAB1 (0.43) | TPSAB1TPSD1TPSG1GAANOS3 | |
| SCHEMBL1773240 | 0.77 | TPSAB1 (0.43) | TPSAB1TPSD1TPSG1GAANOS3 | |
| SCHEMBL8312653 | 0.75 | HPGD (0.49) | TPSAB1TPSD1TPSG1THRB | |
| Acetic Acid SCHEMBL1773187 | 0.75 | KDM4E (0.48) | TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | TPSAB1 3078/4885TPSD1 1933/4885TPSG1 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.