⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070127 | 0.79 | — | — | |
| SCHEMBL2283306 | 0.77 | — | — | |
| SCHEMBL2287850 | 0.74 | — | — | |
| SCHEMBL2288206 | 0.72 | — | — | |
| SCHEMBL2283037 | 0.72 | — | — | |
| SCHEMBL2289124 | 0.72 | — | — | |
| SCHEMBL2283222 | 0.72 | — | — | |
| SCHEMBL2283224 | 0.72 | — | — | |
| SCHEMBL2283444 | 0.72 | — | — | |
| SCHEMBL2283080 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9095601-B2 | Cell permeable nanoconjugates of shell-crosslinked knedel (SCK) and peptide nucleic acids (“PNAs”) with uniquely expressed or over-expressed mRNA targeting sequences for early diagnosis and therapy of cancer | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2015-08-04 | — | — | US | claimed |
| US-20130230452-A1 | CELL PERMEABLE NANOCONJUGATES OF SHELL-CROSSLINKED KNEDEL (SCK) AND PEPTIDE NUCLEIC ACIDS (\"PNAs\") WITH UNIQUELY EXPRESSED OR OVER-EXPRESSED mRNA TARGETING SEQUENCES FOR EARLY DIAGNOSIS AND THERAPY OF CANCER | WASHINGTON UNIVERSITY (US) | 2013-09-05 | — | — | US | claimed |
| EP-1165687-B1 | POLYOXYMETHYLENE RESIN COMPOSITIONS HAVING ENHANCED TENSILE ELONGATION, THERMAL STABILITY AND IMPACT RESISTANCE | KOREA ENG PLASTICS CO LTD (KR) | 2004-12-22 | — | — | EP | claimed |
| US-6096453-A | Polymeric thin-film reversible electrochemical charge storage devices | ADVEN POLYMERS, INC. (US) | 2000-08-01 | — | — | US | claimed |
| WO-1999066572-A1 | POLYMERIC THIN-FILM REVERSIBLE ELECTROCHEMICAL CHARGE STORAGE DEVICES | ADVEN POLYMERS, INC. (US) | 1999-12-23 | — | — | WO | claimed |
| US-4795755-A | ANTISECRETORY, ANTIULCER AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-03 | — | — | US | claimed |
| US-4748165-A | ANTISECRETORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-31 | — | — | US | claimed |
| US-4746672-A | HISTAMINE H-2 ANTAGONISTS WHICH INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (US) | 1988-05-24 | — | — | US | claimed |
| US-4696933-A | INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (GB) | 1987-09-29 | — | — | US | claimed |
| US-4665073-A | HISTAMINE H2-ANTAGONISTS | ICI AMERICAS INC. (GB) | 1987-05-12 | — | — | US | claimed |
| US-4447441-A | ANTIHISTAMINE, ANTIULCER AND ANTISECRETORY AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-08 | — | — | US | claimed |
| EP-0103390-A2 | Guanidine-containing esters as histamine H2 receptor blockers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-21 | — | — | EP | claimed |
| EP-0067508-A1 | Amidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| EP-0061318-A2 | Guanidinoheterocyclic derivatives as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-29 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060730-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060696-A1 | Nitrogen heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060093-A2 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0059597-A2 | Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | claimed |