Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744005 | 1.00 | FFAR4 (0.58) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL17744006 | 1.00 | FFAR4 (0.58) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL22274216 | 1.00 | FFAR4 (0.58) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL17744101 | 0.95 | FFAR1 (0.61) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL17744104 | 0.95 | FFAR1 (0.61) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL22274247 | 0.95 | FFAR1 (0.61) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL17744098 | 0.95 | FFAR1 (0.61) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL22550050 | 0.91 | FFAR1 (0.67) | FFAR4FFAR1FAAHALDH1A1MAPT | |
| SCHEMBL3874930 | 0.90 | FFAR1 (0.70) | FFAR4FFAR1FAAHMAPTPRKCA | |
| SCHEMBL27402994 | 0.90 | FFAR1 (0.56) | FFAR4FFAR1FAAHALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20200080086-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3020701-B1 | NOVEL LIPID | DAIICHI SANKYO CO LTD (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-20180051285-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3020701-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | FFAR4 195/4885FFAR1 183/4885FAAH 513/4885 |
| US-20180051285-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | FFAR4 175/4885FFAR1 161/4885FAAH 748/4885 |
| US-20200080086-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | FFAR4 175/4885FFAR1 161/4885FAAH 748/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | FFAR4 175/4885FFAR1 161/4885FAAH 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.