Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | F7 | P08709 | 5/20 | 0.50 |
| ▸ | F3 | P13726 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16503983 | 1.00 | FFAR1 (0.53) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL17744013 | 1.00 | FFAR1 (0.53) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL23704055 | 1.00 | FFAR1 (0.53) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL15317873 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL44603 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL10133212 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL6037208 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL21197440 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL20603893 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL12186743 | 0.94 | FFAR1 (0.57) | FFAR1FFAR4ALDH1A1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20200080086-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3020701-B1 | NOVEL LIPID | DAIICHI SANKYO CO LTD (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-20180051285-A1 | CATIONIC LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-3020701-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | FFAR1 183/4885FFAR4 195/4885ALDH1A1 1863/4885 |
| US-20180051285-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | FFAR1 161/4885FFAR4 175/4885ALDH1A1 2540/4885 |
| US-20200080086-A1 | CATIONIC LIPID | CETP, NPC1L1, LIPA | FFAR1 161/4885FFAR4 175/4885ALDH1A1 2540/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | FFAR1 161/4885FFAR4 175/4885ALDH1A1 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.