SCHEMBL1774407

SCHEMBL1774407

Nc1ccccc1N(N)N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
ALOX15 P16050 2/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 6/20 0.43
TSHR P16473 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
HSD17B10 Q99714 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HPGD P15428 2/20 0.43
ADRA2B P18089 1/20 0.40
PTGS1 P23219 1/20 0.40
CHEK1 O14757 1/20 0.39
NEK2 P51955 1/20 0.39
LIMK1 P53667 1/20 0.39
DYRK1A Q13627 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7154215 0.97 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29193912 0.81 SMN1; SMN2 (0.35) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL20908971 0.79 CYP3A4 (0.41) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL11238026 0.79 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL20886039 0.78 CYP3A4 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL21733241 0.78 CYP3A4 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL19882358 0.78 CYP3A4 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL19337009 0.78 CHEK1 (0.46) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL5146946 0.77 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL15268120 0.74 CHEK1 (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113634284-A Covalent organic framework catalyst and preparation method and application thereof 安徽省池州生态环境监测中心 2021-11-12 CN claimed
CN-113634284-B Covalent organic framework catalyst and preparation method and application thereof 安徽省池州生态环境监测中心 2023-04-21 CN disclosed
CN-113634284-A Covalent organic framework catalyst and preparation method and application thereof 安徽省池州生态环境监测中心 2021-11-12 CN disclosed
CN-113634284-A Covalent organic framework catalyst and preparation method and application thereof 安徽省池州生态环境监测中心 2021-11-12 CN disclosed
US-20160088835-A1 AGROCHEMICAL OIL DISPERSION FORMULATION, USE OF THE AGROCHEMICAL OIL DISPERSION FORMULATIONS AND PROCESS FOR THE PREPARATION OF THE AGROCHEMICAL OIL DISPERSION FORMULATION OXITENO S.A. INDÚSTRIA E COMÉRCIO (BR) 2016-03-31 US disclosed
EP-2987405-A1 AGROCHEMICAL FORMULATION OF THE OIL DISPERSION TYPE, USE OF THE AGROCHEMICAL FORMULATIONS OF THE OIL DISPERSION TYPE, AND METHOD FOR PRODUCING AN AGROCHEMICAL FORMULATION OF THE OIL DISPERSION TYPE Oxiteno S.A. Industria e Comercio (BR) 2016-02-24 EP disclosed
US-7990602-B2 Display medium and display device FUJI XEROX CO., LTD. (JP) 2011-08-02 US disclosed
US-7944596-B2 Display medium and display device FUJI XEROX CO., LTD. (JP) 2011-05-17 US disclosed
US-20100309538-A1 DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-12-09 US disclosed
US-20100142027-A1 DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-06-10 US disclosed
US-7344778-B2 Powder-coated support and production method thereof FUJIFILM CORPORATION (JP) 2008-03-18 US disclosed
US-20050094059-A1 Display element FUJI PHOTO FILM CO., LTD. 2005-05-05 US disclosed
US-20040058166-A1 Powder-coated support and production method thereof FUJI PHOTO FILM CO., LTD. 2004-03-25 US disclosed
EP-1100484-A1 MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS SmithKline Beecham Corporation (US) 2001-05-23 EP disclosed
WO-2000003704-A1 MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2000-01-27 WO disclosed
EP-0402020-A1 An integrated process for the preparation of methylene diphenylene diisocyanates and polymethylene polyphenylene poly (isocyanates) from diamines and polyamines ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-12-12 EP disclosed