SCHEMBL5146946

SCHEMBL5146946

Nc1ccccc1N(c1ccccc1N)c1ccccc1N(c1ccccc1N)c1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.50
ALOX15 P16050 2/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 6/20 0.43
TSHR P16473 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 2/20 0.43
CHEK1 O14757 1/20 0.39
NEK2 P51955 1/20 0.39
LIMK1 P53667 1/20 0.39
DYRK1A Q13627 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
GAA P10253 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238026 0.97 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29520359 0.83 ALDH1A1 (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL2009250 0.83 ALDH1A1 (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL5493729 0.81 ALDH1A1 (0.52) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL388104 0.81 ALDH1A1 (0.52) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL30221915 0.81 ALDH1A1 (0.52) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL7517260 0.80 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL6314684 0.79 ALDH1A1 (0.58) CYP3A4ALDH1A1TSHRTDP1HSD17B10
SCHEMBL8663873 0.78 ALDH1A1 (0.43) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL1774407 0.77 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050118381-A1 Diimonium salt mixtures, aminium salts mixtures and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-06-02 US claimed
EP-1506956-A1 DIIMONIUM SALT MIXTURES, AMINIUM SALTS MIXTURES AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2005-02-16 EP claimed
EP-1506956-A4 DIIMONIUM SALT MIXTURES, AMINIUM SALTS MIXTURES AND USE THEREOF NIPPON KAYAKU KK (JP) 2007-07-18 EP disclosed
CN-1656059-A Diimonium salt mixtures, aminium salts mixtures and use thereof NIPPON KAYAKU KK (JP) 2005-08-17 CN disclosed
US-20050118381-A1 Diimonium salt mixtures, aminium salts mixtures and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-06-02 US disclosed
US-20050118381-A1 Diimonium salt mixtures, aminium salts mixtures and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-06-02 US disclosed
EP-1506956-A1 DIIMONIUM SALT MIXTURES, AMINIUM SALTS MIXTURES AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2005-02-16 EP disclosed
EP-1506956-A1 DIIMONIUM SALT MIXTURES, AMINIUM SALTS MIXTURES AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2005-02-16 EP disclosed
WO-2003097580-A1 DIIMONIUM SALT MIXTURES, AMINIUM SALTS MIXTURES AND USE THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2003-11-27 WO disclosed