SCHEMBL17744879

SCHEMBL17744879

Nc1ccc(C(=O)Oc2ccc(OC(=O)c3cccc(N)c3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 4/20 0.56
KMT2A Q03164 4/20 0.56
F2 P00734 3/20 0.56
PRSS2 P07478 3/20 0.56
PRSS3 P35030 3/20 0.56
PKM P14618 2/20 0.56
PARP10 Q53GL7 1/20 0.56
NR1H4 Q96RI1 1/20 0.51
MAPT P10636 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
MEN1 O00255 2/20 0.47
PBRM1 Q86U86 1/20 0.47
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29846109 0.97 KMT2A (0.51) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL707848 0.97 KMT2A (0.51) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL26103700 0.93 PBRM1 (0.53) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL29930784 0.93 PBRM1 (0.53) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL30957000 0.92 PRSS1 (0.52) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL17744786 0.92 NR1H4 (0.50) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL22826274 0.90 PRSS1 (0.56) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL8445592 0.90 KMT2A (0.54) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL22826275 0.89 MAPT (0.49) PRSS1KMT2AF2PRSS2PRSS3
SCHEMBL13292752 0.88 MAPT (0.57) PRSS1KMT2AF2PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed