SCHEMBL8445592

SCHEMBL8445592

Nc1ccc(OC(=O)c2cccc(C(=O)Oc3ccc(N)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.54
F2 P00734 2/20 0.54
PRSS1 P07477 2/20 0.54
PRSS2 P07478 2/20 0.54
PRSS3 P35030 2/20 0.54
PKM P14618 2/20 0.54
PARP10 Q53GL7 1/20 0.53
MAPT P10636 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
NR1H4 Q96RI1 1/20 0.49
MEN1 O00255 1/20 0.49
MAPK1 P28482 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
TBXA2R P21731 1/20 0.47
SLC6A2 P23975 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27769736 0.93 PARP10 (0.51) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL29846109 0.93 KMT2A (0.51) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL707848 0.93 KMT2A (0.51) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL14552344 0.92 KMT2A (0.55) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL22826275 0.92 MAPT (0.49) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL17744879 0.90 PRSS1 (0.56) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL30957000 0.89 PRSS1 (0.52) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL26103700 0.89 PBRM1 (0.53) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL29930784 0.89 PBRM1 (0.53) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL12324720 0.87 SMN1; SMN2 (0.52) KMT2AF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108841003-B Polyimide dielectric film and preparation method and application thereof 中国科学院电工研究所 2021-01-12 CN claimed
CN-122029478-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2026-05-12 CN disclosed
CN-120051729-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2025-05-27 CN disclosed
CN-119856108-A Liquid crystal aligning agent and liquid crystal display element 日产化学株式会社 2025-04-18 CN disclosed
CN-115151609-B Polyimide varnish 日产化学株式会社 2025-02-18 CN disclosed
CN-119462652-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2025-02-18 CN disclosed
CN-119212979-A Diamine compound, polymer obtained using same, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-12-27 CN disclosed
CN-119213355-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-12-27 CN disclosed
CN-119096187-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-12-06 CN disclosed
CN-112313571-B Method for manufacturing zero-face anchor film and liquid crystal display element 日产化学株式会社 2024-11-19 CN disclosed
US-20130203895-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-08-08 US disclosed
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-01-10 US disclosed
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-01-10 US disclosed
US-8288591-B2 Curing agents for epoxy resins DESIGNER MOLECULES, INC. (US) 2012-10-16 US disclosed
US-8288591-B2 Curing agents for epoxy resins DESIGNER MOLECULES, INC. (US) 2012-10-16 US disclosed
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2010-06-10 US disclosed
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2010-06-10 US disclosed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A9 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS 1998-09-17 WO disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DOT1L, EHMT1, ASH1L KMT2A 271/4885F2 1820/4885PRSS1 3472/4885
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS PTGER3, PTGER4, ELL KMT2A 669/4885F2 727/4885PRSS1 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.