SCHEMBL1774693

SCHEMBL1774693

COc1c(Cc2cc3ccccc3s2)cc(C2O[C@H](COCc3ccccc3)[C@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 7/20 0.38
SSTR1 P30872 1/20 0.37
SSTR2 P30874 1/20 0.37
SSTR4 P31391 1/20 0.37
SSTR3 P32745 1/20 0.37
SSTR5 P35346 1/20 0.37
SLC5A1 P13866 3/20 0.35
TACR2 P21452 1/20 0.35
HTR1A P08908 1/20 0.35
PTPN1 P18031 4/20 0.34
CDC25B P30305 4/20 0.34
PTPN2 P17706 2/20 0.34
PTPN6 P29350 2/20 0.34
PTPN11 Q06124 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425875 0.87 SLC5A2 (0.44) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL1776327 0.85 SLC5A2 (0.39) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL12425887 0.85 SLC5A2 (0.51) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL2132782 0.85 SSTR1 (0.42) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12425885 0.83 SLC5A2 (0.57) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL12425873 0.83 SLC5A2 (0.38) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL12425956 0.82 SLC5A2 (0.56) SLC5A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL2129836 0.81 PTPN1 (0.41) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12425882 0.81 SLC5A2 (0.49) SLC5A2SLC5A1PTPN1CDC25BPTPN2
SCHEMBL1775540 0.81 SSTR4 (0.37) SLC5A2SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943748-B2 Glucitol derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-05-17 US disclosed
US-20080319047-A1 Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
EP-1803721-A1 NOVEL GLUCITOL DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319047-A1 Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes SLC5A1, SLC5A2, GPR119 SLC5A2 2/4885SSTR1 2006/4885SSTR2 3419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.