Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463615 | 0.92 | CDK1 (0.43) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL915255 | 0.89 | CDK1 (0.38) | CDK1GAA | |
| SCHEMBL121017 | 0.88 | CDK1 (0.52) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL13370005 | 0.88 | CDK1 (0.52) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL21585569 | 0.87 | CDK1 (0.51) | CDK1GAAMAPTTP53GLA | |
| Iodosulfuron SCHEMBL119814 | 0.86 | CDK1 (0.42) | CDK1GAAMAPTKDM4ENPC1 | |
| Iodosulfuron SCHEMBL29355338 | 0.86 | CDK1 (0.42) | CDK1GAAMAPTKDM4ENPC1 | |
| Iodosulfuron SCHEMBL29686924 | 0.86 | CDK1 (0.42) | CDK1GAAMAPTKDM4ENPC1 | |
| Iodosulfuron SCHEMBL7638003 | 0.86 | CDK1 (0.42) | CDK1GAAMAPTKDM4ENPC1 | |
| Iodosulfuron SCHEMBL19463628 | 0.86 | CDK1 (0.48) | CDK1GAAMAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10448638-B2 | Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors | DOW AGROSCIENCES LLC (US) | 2019-10-22 | — | — | US | disclosed |
| WO-2018138498-A1 | NON-TARGET SITE RESISTANCE | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2018-08-02 | — | — | WO | disclosed |
| US-20160135457-A1 | SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS | DOW AGROSCIENCES | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160135457-A1 | SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS | NOTUM, ABAT, SOD1 | CDK1 2922/4885GAA 14/4885MAPT 149/4885 |
| US-10448638-B2 | Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors | NOTUM, ABAT, SOD1 | CDK1 2922/4885GAA 14/4885MAPT 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.