Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 1.00 |
| ▸ | ABCC1 | P33527 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747432 | 0.92 | ABCG2 (0.85) | ABCG2ABCC1MAPTPIM1KDR | |
| SCHEMBL17747488 | 0.92 | ABCG2 (0.85) | ABCG2ABCC1MAPTPIM1KDR | |
| SCHEMBL17747450 | 0.91 | ABCG2 (0.85) | ABCG2ABCC1MAPTALDH1A1HPGD | |
| SCHEMBL17747500 | 0.85 | ABCG2 (0.82) | ABCG2ABCC1MAPTALDH1A1HPGD | |
| SCHEMBL17747448 | 0.85 | ABCG2 (0.84) | ABCG2ABCC1MAPTALDH1A1HPGD | |
| SCHEMBL17747486 | 0.85 | ABCG2 (0.73) | ABCG2ABCC1MAPTPIM1KDR | |
| SCHEMBL17747481 | 0.85 | ABCG2 (0.73) | ABCG2ABCC1MAPTPIM1KDR | |
| SCHEMBL17747475 | 0.85 | ABCG2 (0.73) | ABCG2ABCC1MAPTPIM1KDR | |
| SCHEMBL17747501 | 0.83 | ABCG2 (1.00) | ABCG2ABCC1MAPTALDH1A1HPGD | |
| SCHEMBL17747435 | 0.83 | ABCG2 (0.83) | ABCG2ABCC1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137664-A1 | THIENO [2,3-b] PYRIDINES AS MULTIDRUG RESISTANCE MODULATORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-05-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137664-A1 | THIENO [2,3-b] PYRIDINES AS MULTIDRUG RESISTANCE MODULATORS | ABCC1, ABCB1, MT-CO1 | ABCG2 223/4885ABCC1 1/4885MAPT 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.