Propionic Acid

Propionic Acid

SCHEMBL17748841

C=CC(C)(CCC=C(C)C)OC(=O)CC.CCC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.44
HIF1A Q16665 4/20 0.37
EPAS1 Q99814 4/20 0.37
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29127459 0.95 ALOX15 (0.45) ALOX15HIF1AEPAS1LMNACYP3A4
SCHEMBL538489 0.95 ALOX15 (0.47) ALOX15HIF1AEPAS1LMNACYP3A4
SCHEMBL1870227 0.95 ALOX15 (0.47) ALOX15HIF1AEPAS1LMNACYP3A4
Linalyl Acetate SCHEMBL1471933 0.91 ALOX15 (0.44) ALOX15HIF1AEPAS1LMNACYP3A4
Linalyl Acetate SCHEMBL29127460 0.90 ALOX15 (0.45) ALOX15HIF1AEPAS1LMNACYP3A4
SCHEMBL30883182 0.87 ALOX15 (0.55) ALOX15CYP3A4
SCHEMBL28828747 0.85 ALOX15 (0.44) ALOX15HIF1AEPAS1LMNACYP3A4
SCHEMBL29833566 0.85 ALOX15 (0.36) ALOX15HIF1AEPAS1
SCHEMBL623480 0.84 ALOX15 (0.49) ALOX15HIF1AEPAS1LMNACYP3A4
SCHEMBL8743649 0.84 ALOX15 (0.52) ALOX15HIF1AEPAS1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455284-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2019-03-20 EP disclosed
WO-2017196762-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO disclosed
WO-2017196763-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO disclosed
EP-3218425-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2017-09-20 EP disclosed
WO-2016077513-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2016-05-19 WO disclosed