Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 5/20 | 0.73 |
| ▸ | BRD4 | O60885 | 10/20 | 0.67 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.66 |
| ▸ | TAF1 | P21675 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748909 | 0.84 | CECR2 (0.65) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17748890 | 0.83 | CECR2 (0.75) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL24866050 | 0.83 | BRD4 (0.76) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17748943 | 0.82 | CECR2 (1.00) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17748894 | 0.81 | BRD4 (1.00) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17748893 | 0.80 | BRD9 (0.71) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17756347 | 0.80 | BRD9 (1.00) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL31590527 | 0.79 | BRD4 (0.74) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL31589675 | 0.79 | BRD4 (0.74) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL17748876 | 0.79 | BRD4 (0.74) | CECR2BRD4BRD9TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | claimed |
| EP-3218374-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF BROMODOMAIN | Genentech, Inc. (US) | 2017-09-20 | — | — | EP | claimed |
| WO-2016077380-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | claimed |
| CN-116003409-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-107531692-B | Therapeutic compounds and uses thereof | 基因泰克公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-107108613-B | Bromodomain inhibitors and uses thereof | 基因泰克公司 | 2020-02-25 | — | — | CN | disclosed |
| EP-3218374-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF BROMODOMAIN | Genentech, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016077380-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |