CECR2

Chromatin remodeling regulator CECR2 · Q9BXF3 · CECR2 on Sugi Atlas →

11,865 patent compounds predicted against CECR2, 9,060 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL12177434 SCHEMBL12177434 0.61 11/20
SCHEMBL15067688 SCHEMBL15067688 0.55 9/20
SCHEMBL15647909 SCHEMBL15647909 0.54 8/20
SCHEMBL2485668 SCHEMBL2485668 0.42 8/20
SCHEMBL2112181 SCHEMBL2112181 0.51 7/20
SCHEMBL7454709 SCHEMBL7454709 0.34 6/20
SCHEMBL12177211 SCHEMBL12177211 0.57 5/20
SCHEMBL12177556 SCHEMBL12177556 0.55 5/20
SCHEMBL15957091 SCHEMBL15957091 0.55 5/20
SCHEMBL15957174 SCHEMBL15957174 0.53 5/20
SCHEMBL12177294 SCHEMBL12177294 0.53 5/20
SCHEMBL10667729 SCHEMBL10667729 0.47 5/20
SCHEMBL13005444 SCHEMBL13005444 0.41 5/20
SCHEMBL13629854 SCHEMBL13629854 0.39 5/20
SCHEMBL15957196 SCHEMBL15957196 0.55 4/20
SCHEMBL15956937 SCHEMBL15956937 0.53 4/20
SCHEMBL15956878 SCHEMBL15956878 0.52 4/20
SCHEMBL15956889 SCHEMBL15956889 0.51 4/20
SCHEMBL13329893 SCHEMBL13329893 0.49 4/20
SCHEMBL15069208 SCHEMBL15069208 0.48 4/20

Clinical trials — most relevant to CECR2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer PHASE2UNKNOWN
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab PHASE1/PHASE2RECRUITING
Chidamide Combined With Toripalimab in Sarcoma PHASE2COMPLETED
5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS PHASE2COMPLETED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia nanCOMPLETED
The PRE-OP ENERGY Trial nanUNKNOWN
Sperm Epigenome in Hodgkin Lymphoma nanNOT_YET_RECRUITING
Effect of Exercise Gene Expression and Histone Modifications in Patients With Hemiplegia nanRECRUITING
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Precision High-Intensity Training Through Epigenetics (PHITE) nanCOMPLETED
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients nanCOMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Age Related Chromatin Remodelling as a Therapeutic Target for Organ Protection in Cardiac Surgery nanACTIVE_NOT_RECRUITING
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Genetic of SportS Induced Endofibrotic Remodeling nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Analysis of DNA Methylation in Spondyloarthritis nanCOMPLETED
Genetic Markers of Coronary Heart Disease in Type 2 Diabetes nanCOMPLETED
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal nanCOMPLETED
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Family Resilience Initiative Research Program nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a CECR2 binder may also engage these)

ProteinNameSimilarity
E9Q2Z1 1.000 E9Q2Z1 →
MIDEAS Mitotic deacetylase-associated SANT domain protein 0.997 landscape →
BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 0.994 landscape →
A2AHC3 0.994 A2AHC3 →
Q91YE5 0.994 Q91YE5 →
Q76N89 0.993 Q76N89 →
Q76LL6 0.993 Q76LL6 →
Q9Y2H5 0.993 Q9Y2H5 →
O18805 0.993 O18805 →
Q922B9 0.993 Q922B9 →
Q6PCQ0 0.992 Q6PCQ0 →
P48382 0.992 P48382 →
Q4G112 0.992 Q4G112 →
A7XYJ6 0.992 A7XYJ6 →
Q8BZ32 0.992 Q8BZ32 →
Q8VDP4 0.992 Q8VDP4 →
Q9JL04 0.992 Q9JL04 →
Q8R5I7 0.992 Q8R5I7 →
Q80YR5 0.992 Q80YR5 →
P28322 0.992 P28322 →
A0JPN4 0.991 A0JPN4 →
B2RRE7 0.991 B2RRE7 →
E1BE02 0.991 E1BE02 →
Q9BQK8 0.991 Q9BQK8 →
Q9Y6A5 0.991 Q9Y6A5 →
A7XYH5 0.991 A7XYH5 →
A6QLA6 0.991 A6QLA6 →
NFRKB Nuclear factor related to kappa-B-binding protein 0.991 landscape →
O70405 0.991 O70405 →
Q76I79 0.991 Q76I79 →