Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.64 |
| ▸ | CA1 | P00915 | 9/20 | 0.64 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | CA4 | P22748 | 3/20 | 0.55 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795003 | 0.83 | CA2 (0.64) | CA2CA1CA9CA12CA14 | |
| SCHEMBL246236 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL2181186 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL2005567 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3446128 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| Hydrochloric Acid SCHEMBL19272459 | 0.82 | CA2 (0.64) | CA2CA1CA9CA12CA14 | |
| SCHEMBL185757 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7179836 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL16410190 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL28223875 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943637-B2 | Thienopyridine derivatives and the use thereof as HSP90 modulators | MERCK PATENT GMBH (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20090054452-A1 | Thienopyridine Derivatives and the Use Thereof as Hsp90 Modulators | MERCK PATENT GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054452-A1 | Thienopyridine Derivatives and the Use Thereof as Hsp90 Modulators | HSP90AA1, HSP90AB1, HSP90AB2P | CA2 3625/4885CA1 4690/4885CA9 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.