Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.57 |
| ▸ | CECR2 | Q9BXF3 | 7/20 | 0.57 |
| ▸ | TAF1 | P21675 | 5/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.57 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17753824 | 0.89 | CECR2 (0.58) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL19658513 | 0.77 | CECR2 (0.55) | BRD4CECR2TAF1BRD9 | |
| SCHEMBL17753948 | 0.73 | CECR2 (0.52) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL17753954 | 0.73 | CECR2 (1.00) | BRD4CECR2TAF1BRD9 | |
| SCHEMBL17753953 | 0.73 | CECR2 (0.81) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL17753567 | 0.73 | TAF1 (0.74) | BRD4CECR2TAF1BRD9 | |
| SCHEMBL17752994 | 0.73 | BRD4 (0.65) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL17753970 | 0.73 | BRD4 (0.67) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL17753004 | 0.72 | CECR2 (0.80) | BRD4CECR2TAF1BRD9ATAD2 | |
| SCHEMBL17753001 | 0.71 | TAF1 (0.52) | BRD4CECR2TAF1BRD9ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077375-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |