Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289680 | 1.00 | CA1 (0.35) | CA1CA2CA4CYP2D6CYP19A1 | |
| SCHEMBL18371921 | 1.00 | CA1 (0.35) | CA1CA2CA4CYP2D6CYP19A1 | |
| SCHEMBL19374768 | 1.00 | CA1 (0.35) | CA1CA2CA4CYP2D6CYP19A1 | |
| SCHEMBL21081499 | 1.00 | CA1 (0.35) | CA1CA2CA4CYP2D6CYP19A1 | |
| SCHEMBL18371919 | 1.00 | CA1 (0.35) | CA1CA2CA4CYP2D6CYP19A1 | |
| SCHEMBL10136554 | 0.95 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL18371916 | 0.95 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL18371917 | 0.95 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL788724 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL788707 | 0.84 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765018-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| US-9765018-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160137595-A1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137595-A1 | IDO INHIBITORS | IDO1, IDO2, TDO2 | CA1 3461/4885CA2 2639/4885CA4 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.