Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9575626 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27975811 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6759361 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3280646 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10663595 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL15539230 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27841271 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| SCHEMBL10820897 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| SCHEMBL8558471 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1HTTKMT2AALDH1A1 | |
| SCHEMBL6727148 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9885969-B2 | Carrier for two-component developer, two-component developer, and method of preparing carrier for two-component developer | FUJI XEROX CO., LTD. (JP) | 2018-02-06 | — | — | US | disclosed |
| US-9864293-B2 | Electrostatic charge image developing carrier, method of preparing electrostatic charge image developing carrier, and electrostatic charge image developer | FUJI XEROX CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-20170277054-A1 | CARRIER FOR TWO-COMPONENT DEVELOPER, TWO-COMPONENT DEVELOPER, AND METHOD OF PREPARING CARRIER FOR TWO-COMPONENT DEVELOPER | FUJI XEROX CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170255120-A1 | ELECTROSTATIC CHARGE IMAGE DEVELOPING CARRIER, METHOD OF PREPARING ELECTROSTATIC CHARGE IMAGE DEVELOPING CARRIER, AND ELECTROSTATIC CHARGE IMAGE DEVELOPER | FUJI XEROX CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
| US-7989130-B2 | Electrostatic latent image developing toner, manufacturing method for electrostatic latent image developing toner, electrostatic latent image developing developer, and image forming method | FUJI XEROX CO., LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7951519-B2 | Toner for development of electrostatic image, method for manufacturing the same, developer for development of electrostatic image, toner cartridge, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-7943280-B2 | Toner containing a laminar inorganic mineral in which part or all of the ions present between layers are modified by organic ions | RICOH COMPANY, LTD. (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-2040126-B1 | Toner for Development of Electrostatic Image, Developer for Development of Electrostatic Image, Toner Cartridge, Process Cartridge, and Image Forming Apparatus | FUJI XEROX CO LTD (JP) | 2011-05-11 | — | — | EP | disclosed |
| EP-1835350-B1 | Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method | RICOH CO LTD (JP) | 2011-05-11 | — | — | EP | disclosed |
| US-7901857-B2 | Electrostatic latent image developing toner, production method thereof, electrostatic latent image developer, and image forming method | FUJI XEROX CO., LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-7364826-B2 | Electrostatic latent image developing toner, and method for manufacturing electrostatic latent image developer and electrostatic latent image developing toner | FUJI XEROX CO., LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20080013987-A1 | Toner for electrostatic image development, manufacturing method thereof, electrostatic image developer and image forming method | FUJI XEROX CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-20070218380-A1 | TONER | RICOH COMPANY, LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1835350-A1 | Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method | Ricoh Company, Ltd. (JP) | 2007-09-19 | — | — | EP | disclosed |
| US-20070020541-A1 | Electrostatic latent image developing toner, manufacturing method for electrostatic latent image developing toner, electrostatic latent image developing developer, and image forming method | FUJI XEROX CO., LTD. (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060210899-A1 | Electrostatic latent image developing toner, production method thereof, electrostatic latent image developer, and image forming method | FUJI XEROX CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060115757-A1 | Toner for development of electrostatic latent image, electrostatic latent image developer, and method for formation of image | FUJI XEROX CO., LTD. (JP) | 2006-06-01 | — | — | US | disclosed |
| US-20060046178-A1 | Electrostatic latent image developing magenta toner, electrostatic latent image developer, toner manufacturing method, and image forming method | FUJI XEROX CO., LTD. (JP) | 2006-03-02 | — | — | US | disclosed |
| US-20050181295-A1 | Electrostatic latent image developing toner, and method for manufacturing electrostatic latent image developer and electrostatic latent image developing toner | FUJI XEROX CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| US-20040058262-A1 | Toner and image forming method using the same and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |