Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCL5 | P13501 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232864 | 0.83 | EPHX2 (0.41) | EPHX2MEN1KMT2ACCL5CCR5 | |
| SCHEMBL18074013 | 0.83 | EPHX2 (0.41) | EPHX2MEN1KMT2ACCL5CCR5 | |
| SCHEMBL20756318 | 0.80 | MEN1 (0.44) | EPHX2MEN1KMT2A | |
| SCHEMBL23261695 | 0.78 | EPHX2 (0.44) | EPHX2MEN1KMT2A | |
| SCHEMBL8077317 | 0.78 | TSHR (0.37) | MEN1KMT2A | |
| SCHEMBL13154408 | 0.78 | EPHX2 (0.35) | EPHX2MEN1KMT2A | |
| SCHEMBL2603251 | 0.77 | EPHX2 (0.46) | EPHX2MEN1KMT2ACCL5CCR5 | |
| SCHEMBL21025379 | 0.76 | POLB (0.37) | — | |
| SCHEMBL19869617 | 0.76 | EPHX2 (0.38) | EPHX2MEN1KMT2A | |
| SCHEMBL10119969 | 0.74 | HCRTR2 (0.32) | CCL5CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | EPHX2 3022/4885MEN1 1076/4885KMT2A 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.