Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17757143 | 0.90 | MAPK7 (0.34) | — | |
| SCHEMBL17757142 | 0.86 | OPRM1 (0.33) | — | |
| SCHEMBL21982520 | 0.79 | — | — | |
| SCHEMBL17757502 | 0.77 | CCNT1 (0.38) | — | |
| SCHEMBL17757144 | 0.77 | CCNT1 (0.33) | — | |
| SCHEMBL17757678 | 0.77 | — | — | |
| SCHEMBL17757659 | 0.76 | CCNT1 (0.40) | — | |
| SCHEMBL17757674 | 0.76 | HRH4 (0.31) | — | |
| SCHEMBL17757671 | 0.75 | GRM2 (0.36) | — | |
| SCHEMBL17757139 | 0.75 | CDK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016075137-A1 | SPIROPYRAZINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2016-05-19 | — | — | WO | disclosed |